miRNA-ISH for Cancer of Unknown Primary
miRNA-ISH for Cancer of Unknown Primary Summary: World-wide approximately 5% of all cancers are determined to have an occult or unknown primary location, upon initial assessment, prior to completing a full pathology report. [Oien] Unfortunately in 20-50% of CUP cases...
MicroRNA in situ Hybridization for Cancer Diagnosis
MicroRNA in situ hybridization for cancer diagnosis Summary: MicroRNAs (miRNA) are approximately 19–24 nucleotides in length and base-pair to complementary sites within messenger RNA (mRNA). Aided by the “RISC” complex this binding functions to promote down-regulation...
Benchtop fully automated All-in-One ten slide system for Fluorescence in situ hybridization (FISH), ISH, miRNA and IHC
We are pleased to bring you the BioGenex NanoVIP a fully automated bench-top integrated system with visualization kits for fluorescence in situ hybridization (FISH), in situ hybridization (ISH), miRNA ISH, and immunohistochemistry (IHC). The compact 10-slide design...
Fluorescent in situ Hybridization (FISH) – Made Easy
We are pleased to introduce the BioGenex eFISH system. This system consist of high specificity eFISH probes, visualization kits, ancillary reagents, in addition to our brand new automated systems: Xmatrx® NANO, and NanoVIP, and our manual system Xmatrx® MINI. This...
EZ-AR2 Elegance – All-in-One and All-at-Once Antigen Retrieval solution
Antigen Retrieval: Antigen retrieval is an effective method of unmasking antigenic epitopes on the surface of formalin-fixed paraffin-embedded (FFPE) tissue sections. The antigen retrieval technique breaks the methylene bridges between epitopes and unrelated proteins...
FISH: Applications in Cancer Diagnostics
In our previous article, we described about the molecular genetic technique of FISH and enumerated its many advantages in cancer diagnostics. Please refer to FISH in molecular cancer diagnostics: the whats and whys?...
FISH in molecular cancer diagnostics: the whats and whys?
Fluorescence in situ hybridization (FISH) – a relatively new cytogenetic technique - is a DNA hybridization-based technique that generally uses directly-labeled fluorescent DNA probes to target specific chromosomal locations within the nucleus, resulting in colored...
Xmatrx® Elite – All-in-One & All-at-Once complete workflow solution! – For Your Tissue Diagnostics Needs!!
High-throughput and automation are the keywords in any cancer diagnostic lab – our Xmatrx® series are just that and more! Xmatrx Elite is versatile for any slide-based staining – IHC, ISH, FISH, multiplex IHC, in situ PCR, micro-RNA, and special staining (SS). Crisp...
i6000 – the workhorse of a pathology lab! – (Interface for both clinical and research diagnostics)
When it comes to cancer diagnostics, tissue-based staining is still the gold standard of diagnostic workflow. And when there are thousands of cancer patients – worldwide - waiting eagerly for “their life and death question”, there is no luxury of time! Everyday there...