miRNA-ISH for Cancer of Unknown Primary

miRNA-ISH for Cancer of Unknown Primary

miRNA-ISH for Cancer of Unknown Primary Summary: World-wide approximately 5% of all cancers are determined to have an occult or unknown primary location, upon initial assessment, prior to completing a full pathology report. [Oien] Unfortunately in 20-50% of CUP cases...

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MicroRNA in situ Hybridization for Cancer Diagnosis

MicroRNA in situ Hybridization for Cancer Diagnosis

MicroRNA in situ hybridization for cancer diagnosis Summary: MicroRNAs (miRNA) are approximately 19–24 nucleotides in length and base-pair to complementary sites within messenger RNA (mRNA). Aided by the “RISC” complex this binding functions to promote down-regulation...

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Fluorescent in situ Hybridization (FISH) – Made Easy

Fluorescent in situ Hybridization (FISH) – Made Easy

We are pleased to introduce the BioGenex eFISH system. This system consist of high specificity eFISH probes, visualization kits, ancillary reagents, in addition to our brand new automated systems: Xmatrx® NANO, and NanoVIP, and our manual system Xmatrx® MINI. This...

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FISH: Applications in Cancer Diagnostics

FISH: Applications in Cancer Diagnostics

In our previous article, we described about the molecular genetic technique of FISH and enumerated its many advantages in cancer diagnostics. Please refer to FISH in molecular cancer diagnostics: the whats and whys?...

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FISH in molecular cancer diagnostics: the whats and whys?

FISH in molecular cancer diagnostics: the whats and whys?

Fluorescence in situ hybridization (FISH) – a relatively new cytogenetic technique - is a DNA hybridization-based technique that generally uses directly-labeled fluorescent DNA probes to target specific chromosomal locations within the nucleus, resulting in colored...

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